Clinical trials of p-(di-2-chloroethylamino)-phenylbutyric acid (CB 1348) in malignant lymphoma.
نویسندگان
چکیده
Everett, Roberts, and Ross (1953) synthesized a series of water-soluble aromatic nitrogen mustards, one of which, p-(di-2-chloroethylamino)-phenylbutyric acid (CB 1348), was found to be a powerful inhibitor of the transplanted Walker rat tumour 256 (Haddow, 1952) and was submitted for clinical trial. Ninety-three patients suffering from advanced carcinoma and from lymphomas have been treated with CB 1348 since September, 1952. This report concerns only the cases of malignant lymphoma, of which there
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ورودعنوان ژورنال:
- British medical journal
دوره 2 4949 شماره
صفحات -
تاریخ انتشار 1955